888-451-4321| Drug Name: | Zithromax |
| Tablet Strength: | 500 mg, 250 mg, 100 mg |
| Best Price: | $0.44 |
| Payment: | Visa, MasterCard, Bitcoin |
| Shipment: | Trackable Courier Service (5-9 days) |
| Where to Buy | Visit CanadaPharmacy |
Active ingredient in the drug Zithromax-an antibiotic of group of macroleads azithromycin.
Contacts 50S a subunit of ribosomes, oppresses to a peptidtranslokaz at a stage of broadcasting and suppresses protein biosynthesis, slowing down growth and reproduction of bacteria, at high concentrations the bactericidal effect is possible.
The action spectrum wide also includes gram-positive, except steady against erythromycin, and gram-negative microorganisms, anaerobe bacterias, chlamydias, mycobacteria, mycoplasmas, ureaplasmas, spirochetes.
It is steady in acid medium, lipophilic, at oral administration it is quickly soaked up from a GIT. After a single dose in 500 mg bioavailability — 37% (effect of “the first passing”), Cmax (0.4 mg/l) is created in 2–3 h, the seeming distribution volume — 31.1 l/kg, linking with proteins in inverse proportion to concentration in blood and is 7–50%, T1/2 — 68 h. Stable level in plasma is reached in 5–7 days. Easily passes gistogematichesky barriers and comes to fabrics.
Substance Azithromycin aplication
For intake: infections top (streptococcal pharyngitis / tonsillitis) and lower (bacterial bronchitis, intersticial and alveolar pneumonia, exacerbation of chronic bronchitis) departments of airways, ENT organs (average otitis, laryngitis and sinusitis), an urinogenital system (an urethritis and a cervicitis), skin and soft tissues (an ugly face, impetigo, the secondary infected dermatosis), a chronic stage of the migrating erythema (Lyme’s disease), the diseases of a stomach and a duodenum associated with Helicobacter pylori.
For infusions: the heavy infections caused by sensitive strains of microorganisms: community-acquired pneumonia, infectious and inflammatory diseases of bodies of a small pelvis.
Contraindications
Hypersensitivity (including to other macroleads), heavy abnormal liver functions and/or kidneys, age till 16 flyings (infusion), till 12 flyings at body weight less than 45 kg (capsules, tablets), up to 6 months (suspension for intake).
Restrictions to use
Abnormal liver function and/or kidneys, arrhythmia or predisposition to arrhythmia and lengthening of an interval of QT.
Use at pregnancy and feeding by a breast
At pregnancy it is possible if the expected effect of therapy exceeds potential risk for a fruit.
Category of action on a fruit on FDA — B.
For the period of treatment it is necessary to stop breastfeeding.
Side effects of the substance Azithromycin
From a nervous system and sense bodys: dizziness, vertigo, headache, paresthesia, excitement, increased fatigue, drowsiness.
From a cardiovascular system and blood (a hemopoiesis, a hemostasis): thorax pain, heartbeat.
From bodies of a GIT: nausea, vomiting, diarrhea, meteorism, abdominal pain, increase in activity of ALT and nuclear heating plant, bilirubin level, cholestasia, jaundice.
From an urinogenital system: vaginal candidiasis, nephrite.
Allergic reactions: rash, itch, urticaria; seldom — a Quincke’s disease, an acute anaphylaxis.
Others: photosensitization, eosinophilia, tranzitorny neutrophilia; at to in introduction (in addition) — a bronchospasm, pain and inflammation in the place of an injection.